MEKK1-MKK4-JNK-AP1 Pathway Negatively Regulates Rgs4 Expression in Colonic Smooth Muscle Cells | PLOS ONE
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Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity | PNAS
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Increased MKK4 Abundance with Replicative Senescence Is Linked to the Joint Reduction of Multiple MicroRNAs | Science Signaling
![Stress-activated JNK pathway. The central MAPKKK (MLK), MAPKK (MKK4/7),... | Download Scientific Diagram Stress-activated JNK pathway. The central MAPKKK (MLK), MAPKK (MKK4/7),... | Download Scientific Diagram](https://www.researchgate.net/publication/47934224/figure/fig8/AS:668270239707145@1536339449766/Stress-activated-JNK-pathway-The-central-MAPKKK-MLK-MAPKK-MKK4-7-MAPK-JNK.png)
Stress-activated JNK pathway. The central MAPKKK (MLK), MAPKK (MKK4/7),... | Download Scientific Diagram
A Non-Redundant Role for Drosophila Mkk4 and Hemipterous/Mkk7 in TAK1-Mediated Activation of JNK | PLOS ONE
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Arabidopsis E3 ligase KEG associates with and ubiquitinates MKK4 and MKK5 to regulate plant immunity - Gao - 2021 - Journal of Integrative Plant Biology - Wiley Online Library
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A Vaccinia Virus-Driven Interplay between the MKK4/7-JNK1/2 Pathway and Cytoskeleton Reorganization | Journal of Virology
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Mkk4 Is a Negative Regulator of the Transforming Growth Factor Beta 1 Signaling Associated With Atrial Remodeling and Arrhythmogenesis With Age | Journal of the American Heart Association
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A Docking Site in MKK4 Mediates High Affinity Binding to JNK MAPKs and Competes with Similar Docking Sites in JNK Substrates* - Journal of Biological Chemistry
![Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity | PNAS Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity | PNAS](https://www.pnas.org/cms/10.1073/pnas.94.7.3004/asset/c7bd61f3-4554-4182-9a49-18c470ea228b/assets/graphic/pq0770168002.jpeg)
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity | PNAS
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